Searchable abstracts of presentations at key conferences in endocrinology

ea0016p458 | Neuroendocrinology | ECE2008

Effect of GH replacement on coronary flow reserve (CFR) and on some cardiovascular risk factors in adult GHD patients

Boschetti Mara , Agosti Sergio , Albanese Valeria , Casalino Laura , Vera Lara , Goglia Umberto , Paolo Bezante Gian , Ferone Diego , Minuto Francesco

GH deficiency (GHD) negatively influences cardiovascular function directly by impairing cardiac filling, performance, and contractility and indirectly by inducing atherosclerotic changes, hypercoagulability, abdominal obesity, insulin resistance, dislipidemia, endothelial dysfunction, etc. This accounts for the reduced life expectancy and increased risk of death for vascular disease in these patients.CFR represents the capacity of the coronary circulatio...